In Civil 3D 2013 (with or without hotfix 2.1), use the PLOT command and use the Window option. While being prompted for the window corners, use the middle button mouse wheel to zoom to locate the exact point you want. Civil 3D then enters a loop in which it displays:

Document “drawing name” has a command in progress.
Hit enter to cancel or [Retry]:

At this point, the user can do nothing with the program. Hitting Enter, Esc, R, etc. or doing more all do nothing except cause the message to be redisplayed. Picking a point or further wheel zooming does nothing useful. Using the application’s red X, or attempting to use the Taskbar to close it are equally ineffectual. The user has no alternative but to terminate Civil 3D using Task Manager, losing all unsaved work in all drawings.

This happens for me in Windows 7 64-bit. It does not occur using AutoCAD 2013 on the same system. Does it happen for you?